What is the half life of tinidazole?

What is the half life of tinidazole?

Elimination The plasma half-life of tinidazole is approximately 12-14 hours. Tinidazole is excreted by the liver and the kidneys. Tinidazole is excreted in the urine mainly as unchanged drug (approximately 20-25% of the administered dose).

Can I drink 2 days after tinidazole?

Do not drink alcohol while taking tinidazole and for at least 3 days after your treatment ends. You may have unpleasant side effects such as fast heartbeats, severe nausea, vomiting, sweating, and warmth or tingling under your skin.

Is tinidazole stronger than metronidazole?

metronidazole, respectively. The Sanz-Sanz study produced efficacy rates of 65% and 74% for tinidazole vs. metronidazole, respectively. Although a single 2g dose of tinidazole appears more effective than a single 2g dose of metronidazole, it may be slightly less effective than seven days of metronidazole.

Do I take all 4 tinidazole at once?

As a guide, a single dose of four tablets taken at the same time is sufficient for most vaginal or dental infections in adults. For other bacterial infections, you are likely to be asked to take a course of treatment which could last up to seven days.

How long does metronidazole take to get out of your system?

by Drugs.com The elimination half life of metronidazole is approximately 8 hours. It takes 5.5 x elimination half life for a medicine to be completely cleared from the body. Therefore it will take about 44 hours (5.5 x 8 hrs) for it to be cleared from your system.

How long does tinidazole take to work for BV?

For bacterial vaginosis, the tinidazole dose is 2 g once daily for two days or 1 g once daily for five days, which is a less frequent and shorter regimen than metronidazole 500 mg twice daily for seven days. Patients should take tinidazole with food to minimize the gastrointestinal adverse effects.

What happens if you mix tinidazole and alcohol?

Consumption of alcoholic beverages or products containing alcohol or propylene glycol during treatment with tinidazole may occasionally trigger a reaction in some patients similar to the disulfiram reaction, which includes unpleasant effects such as flushing, throbbing in head and neck, throbbing headache, difficulty …

Can you drink wine on tinidazole?

You should not drink alcoholic beverages or use medicines that contain a large amount of alcohol while taking Tinidazole. Also continue to avoid Alcohol for about 3 days after stopping Tinidazole.

Why won’t my BV go away after treatment?

Around a third of women who take antibiotic treatment for bacterial vaginosis (BV) find that the problem recurs within the next two to three months. Some strains of BV organisms may have resistance to some antibiotics. You should return to your healthcare provider and describe the problems you are having.

Is tinidazole good for BV?

Tinidazole is generally an expensive alternative to metronidazole for the treatment of trichomoniasis and bacterial vaginosis. It offers little, if any, advantage with regard to safety, tolerability, and effectiveness; however, its once-daily dosing and shorter course of therapy may be useful for some patients.

How long does it take for tinidazole to cure BV?

Does tinidazole cure BV?

Oral tinidazole has been used to treat bacterial vaginosis for over 25 years but in a number of different dosage regimens. Placebo controlled trials have consistently shown increases in cure rate with tinidazole.

How long can you take 4 tablets of tinidazole?

As a guide, a single dose of four tablets taken at the same time is sufficient for most vaginal or dental infections in adults. For other bacterial infections, you are likely to be asked to take a course of treatment which could last up to seven days.

When to go to the ER for tinidazole?

Tinidazole side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as: fever, chills, body aches, flu symptoms; seizure (convulsions).

What does tinidazole do to bacteria and parasites?

Tinidazole (Tindamax) is a nitroimidazole antibiotic. It damages the DNA of bacteria and parasites and prevents them from making new DNA. By doing so, tinidazole (Tindamax) causes bacterial and parasitic cell death and stops them from growing.

How often can you take tinidazole for bacterial vaginosis?

Bacterial vaginosis: There are 2 ways to take tinidazole (Tindamax) for bacterial vaginosis. You can either take 2 grams of tinidazole (Tindamax) by mouth once a day with food for 2 days or you can take 1 gram by mouth once a day with food for 5 days. Is tinidazole (Tindamax) better for bacterial vaginosis than metronidazole?