Can Strattera cause elevated liver enzymes?

Can Strattera cause elevated liver enzymes?

Hepatotoxicity. Atomoxetine has been linked to serum aminotransferase elevations in a small proportion of patients (~0.5%). More importantly, there have been several reports of clinically apparent acute liver injury due to atomoxetine. The onset of injury was within 3 to 12 weeks of starting the medication.

What are the long term effects of Strattera?

Strattera can cause serious heart-related complications (e.g., heart attack, stroke), high blood pressure and increased heart rate especially if you have a history of heart and/or vessel disease and/or irregular heart rate.

Is Strattera hepatotoxic?

Dec. 20, 2004 — The U.S. Food and Drug Administration (FDA) has warned healthcare professionals via a talk paper of changes to the safety labeling for atomoxetine (Strattera, made by Eli Lilly), warning of the risk of hepatotoxicity that may be associated with its use.

Can guanfacine cause liver problems?

Furthermore, despite widescale use of the agent for both hypertension and ADHD, there have been no reports of clinically apparent liver injury attributable to guanfacine. Thus, significant liver injury from guanfacine must be quite rare, if it exists at all.

Is Vyvanse bad for the liver?

Liver problems – Long-term liver damage has been known to occur in people who continually abuse Vyvanse. They may begin to notice fatigue, itching, confusion and a yellow tint to their skin and eyes. Kidney problems – The kidneys’ job is to create urine and remove waste from the blood.

Can you take Strattera for life?

Due to Strattera’s relatively short half-life, it does not stay in patients’ systems for long. It is important to note, though, that every patient has a physiology unique to them, and it may take longer for Strattera to be removed from some patients’ systems than others.

What is the safest drug for ADHD?

Articles On ADHD Medications Side Effects It may take some time to find the best combination. Medications may not work for all ADHD symptoms or affect everyone the same way. A combination of medication, therapy, behavior changes, and skills training is often the most effective treatment.

How long should you take Strattera?

Strattera can be taken with or without food. How long does it usually take for Strattera to work? Some people report small changes in hyperactivity and impulse control within two weeks, but it may take 4 to 8 weeks for the drug to achieve maximum effectiveness.

Does guanfacine cause liver damage?

Mechanism of Injury The mechanism by which guanfacine might cause liver injury is unknown. Guanfacine is metabolized in the liver by the cytochrome P450 system, predominantly CYP 3A4 and production of a toxic intermediate or immunogenic byproduct are reasonable explanations.

Can guanfacine cause brain damage?

This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.

What are the symptoms of liver damage with Strattera?

Rarely, severe liver damage has been associated with Strattera. Liver function tests should be ordered if liver damage is suspected (symptoms include widespread itch, dark urine, yellowing of the skin, right upper abdominal pain, or unexplained “flu” like symptoms).

What should you know about the drug Strattera?

Strattera has been associated with an increased risk of suicidal thoughts or behavior in children and adolescents with ADHD. Talk with your doctor if you notice any worrying change in mood or behavior in a child or adolescent prescribed Strattera.

How long does it take Strattera to work on ADHD?

The full effects of Strattera on ADHD symptoms may take several weeks to develop. The dosage of Strattera should be adjusted in people with liver impairment.

When does Strattera reach its maximum plasma concentration?

Strattera is well absorbed after oral administration and maximal plasma concentrations are reached approximately one to two hours after dosing. Food does not affect the absorption of Strattera.