Table of Contents
- 1 What protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?
- 2 Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active?
- 3 Which of the following occurs during S phase?
- 4 Which of the following events occurs during interphase of the cell cycle?
- 5 What is the most likely pathway taken by a newly synthesized protein that will be secreted by a cell?
- 6 How are cyclins synthesized?
What protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?
cyclin
cyclin: Cyclins are expressed during a specific cell cycle phase. Accordingly, they are classified as M cyclin, S cyclin, G1/S cyclin and G1 cyclin. They bind to specific kinases called cyclin-dependent kinase (CDK) to form a functional complex.
Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active?
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Question | Answer |
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35. Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active | • Cdk |
36. Which of the following triggers the cell’s passage past the G2 checkpoint into mitosis | • MPF |
What is the name of proteins that are involved in the regulation of the cell cycle and that show fluctuations in concentration during the cell cycle?
Two groups of proteins, called cyclins and cyclin-dependent kinases (Cdks), are responsible for the progress of the cell through the various checkpoints. The levels of the four cyclin proteins fluctuate throughout the cell cycle in a predictable pattern (Figure 2).
In which phase of cell cycle are cyclins synthesized?
G1 phase
Thus cells synthesize G1- and G1/S-cyclins during the G1 phase, and they produce M-cyclin molecules during the G2 phase. Cyclin degradation is essential for progression through the cell cycle. Specific enzymes break down cyclins at predefined times during the cell cycle.
Which of the following occurs during S phase?
The most important event occurring in S phase is the replication of DNA. The aim of this process is to produce double the amount of DNA, providing the basis for the chromosome sets of the daughter cells.
Which of the following events occurs during interphase of the cell cycle?
During interphase, the cell grows and makes a copy of its DNA. During the mitotic (M) phase, the cell separates its DNA into two sets and divides its cytoplasm, forming two new cells.
Which is a protein maintained at constant levels throughout the cell cycle?
Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active? cyclins.
What are two types of proteins that regulate the cell cycle?
What is the most likely pathway taken by a newly synthesized protein that will be secreted by a cell?
The most common secretion pathway is the secretory pathway (Figure 1). Newly synthetized proteins are transported from the endoplasmic reticulum (ER), passing the Golgi apparatus and packed into vesicles. The vesicles are then transported to the plasma membrane.
How are cyclins synthesized?
Cyclins are named such because they undergo a constant cycle of synthesis and degradation during cell division. When cyclins are synthesized, they act as an activating protein and bind to Cdks forming a cyclin-Cdk complex. This complex then acts as a signal to the cell to pass to the next cell cycle phase.
Which of the following occurs at specific times in the cell cycle?
At specific times in the cell cycle, M and S cyclins are ubiquitylated and degraded in proteasomes. The anaphase-promoting complex plays an important role in this process by ubiquitylating these cyclins, providing the molecular tag that directs proteins to the proteasome.
Which of the following is synthesized during S phase of cell cycle?
During the S phase, DNA is synthesized in the process of DNA replication. In the meiotic cycle, interphase is split into interphase I and interphase II.