What is the use of ER in a cell?

What is the use of ER in a cell?

The endoplasmic reticulum (ER) is the largest membrane-bound organelle in eukaryotic cells and performs a variety of essential cellular functions, including protein synthesis and processing, lipid synthesis, and calcium (Ca2+) storage and release.

Can a cell survive without the ER?

Answer: Without the ER the cell is not able to synthesis new plasma membrane proteins, lysosomal enzymes, proteines for the Golgi apparatus and proteins for extracellular secretion. In the absence of these cellular mechanisms the cell would probably die.

What would happen to a cell without ER?

If the ER is absent, the skeletal muscle fibers would not be able to contract muscles. Consequently, in the absence of all these basic and essential cellular activities, the cells tend to die.

What is the main function of ER?

The endoplasmic reticulum can either be smooth or rough, and in general its function is to produce proteins for the rest of the cell to function.

What is ER and its function?

The endoplasmic reticulum (ER) is a large, dynamic structure that serves many roles in the cell including calcium storage, protein synthesis and lipid metabolism. The diverse functions of the ER are performed by distinct domains; consisting of tubules, sheets and the nuclear envelope.

What will happen if ER is removed?

endoplasmic reticulum serves many functions. thus, without it,all those functions would vanish leaving the cell incapable to manage properly resulting in death.

What is the function of the rough ER?

The endoplasmic reticulum can either be smooth or rough, and in general its function is to produce proteins for the rest of the cell to function. The rough endoplasmic reticulum has on it ribosomes, which are small, round organelles whose function it is to make those proteins.

Why is smooth ER important?

The smooth ER is important in the synthesis of lipids, such as cholesterol and phospholipids, which form all the membranes of the organism. In addition it is important for the synthesis and secretion of steroid hormones from cholesterol and other lipid precursors.

What happens if the ER malfunctions?

A malfunction of the ER stress response caused by aging, genetic mutations, or environmental factors can result in various diseases such as diabetes, inflammation, and neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, and bipolar disorder, which are collectively known as ‘conformational …

What makes up the ER of a cell?

The ER consists of the nuclear envelope and the peripheral ER, which includes smooth tubules and rough sheets. While the ER is defined as an interconnected network with a continuous membrane, the different structures that make up the ER perform very diverse and specialized functions within the cell.

What makes the ER different from other reticulums?

The ER can be classified in two functionally distinct forms: smooth endoplasmic reticulum (SER) and rough endoplasmic reticulum (RER). The morphological distinction between the two is the presence of protein-synthesizing particles, called ribosomes, attached to the outer surface of the RER.

How does the rough ER control protein processing?

The proximity of the rough ER to the cell nucleus gives the ER unique control over protein processing. The rough ER is able to rapidly send signals to the nucleus when problems in protein synthesis and folding occur and thereby influences the overall rate of protein translation.

What is the function of the ribosomes on rough ER?

The ribosomes on rough ER specialize in the synthesis of proteins that possess a signal sequence that directs them specifically to the ER for processing. (A number of other proteins in a cell, including those destined for the nucleus and mitochondria, are targeted for synthesis on free ribosomes,…