Is Epstein-Barr lytic or lysogenic?

Is Epstein-Barr lytic or lysogenic?

Epstein-Barr virus, which mainly infects B cells and epithelial cells, has two modes of infection: latent and lytic. Epstein-Barr virus infection is predominantly latent; however, lytic infection is detected in healthy seropositive individuals and becomes more prominent in certain pathological conditions.

What are the stages of EBV?

For EBV we have a six-stage model of infection (naive Blast, GC, memory, Immediate early lytic, Early lytic and Late lytic) where each stage may or may not be regulated by the immune response.

Is mono Epstein-Barr?

About Infectious Mononucleosis. Infectious mononucleosis, also called “mono,” is a contagious disease. Epstein-Barr virus (EBV) is the most common cause of infectious mononucleosis, but other viruses can also cause this disease. It is common among teenagers and young adults, especially college students.

What is the lytic and lysogenic cycle?

The lytic cycle involves the reproduction of viruses using a host cell to manufacture more viruses; the viruses then burst out of the cell. The lysogenic cycle involves the incorporation of the viral genome into the host cell genome, infecting it from within.

What is the causative agent of mononucleosis?

Epstein-Barr virus (EBV) is the most common cause of infectious mononucleosis, but other viruses can also cause this disease. It is common among teenagers and young adults, especially college students. At least one out of four teenagers and young adults who get infected with EBV will develop infectious mononucleosis.

How does EBV go latent?

EBV primarily infects the human oropharynx epithelial cells, and then replicates and spreads to B cells, resulting in latent infection in B cells, epithelial cells and natural killer/T cells after extensive host T-cell immune surveillance. Latent EBV infection substantially causes many human malignancies.

Is it possible for an adult to get mononucleosis?

Although the symptoms of mononucleosis are uncomfortable, the infection resolves on its own without long-term effects. Most adults have been exposed to the Epstein-Barr virus and have built up antibodies. Therefore, they’re immune and won’t get mononucleosis.

How long does the incubation period for mononucleosis last?

The incubation period refers to how long before your symptoms appear after being exposed to the virus. Signs and symptoms such as a fever and sore throat usually lessen within a couple of weeks. But fatigue, enlarged lymph nodes and a swollen spleen may last for a few weeks longer.

What happens to red blood cells with mononucleosis?

Mononucleosis can also result in less common complications, including: Anemia — a decrease in red blood cells and in hemoglobin, an iron-rich protein in red blood cells Thrombocytopenia — a low count of platelets, which are blood cells involved in clotting

How does the lytic cycle work in herpesvirus?

Lytic cycle (productive) herpesviral DNA replication Requires: Lytic origin of replication (“ori Lyt ”) + 7 viral proteins that participate directly at replication fork. Rolling circle replication Cleavage of genome concatemers into single units Produces linear genomes that are packaged into capsids